No. BB-00427-02-12
Composition
1–5×10⁹ viable bacteria of the genus Enterococcus faecalis; 1–5×10⁷ viable bacteria of the genus Lactobacillus salivarius; 1–5×10⁸ viable bacteria Bacillus subtilis; water-soluble chitosan 20%; enzymatic peptone 30%; ground sugar up to 100%; water prepared using “Yodis+Se” concentrate according to TU U 14326060.003-98.
Pharmaceutical form
Powder from grey-yellow to grey-brown color.
Main physico-chemical properties
The preparation is highly soluble in water and aqueous solutions.
Pharmacological properties
The preparation exhibits antagonistic activity against a wide range of pathogenic bacteria and fungi. By forming normal microflora, it normalizes secretory immunity and metabolism, stabilizing the body’s defenses. Rapid and directed formation of microbiocenosis in the small (main focus on the duodenum) and large intestine by periodic (from the first day and then once a month) oral administration of a certain amount of beneficial bacteria. It has pronounced antioxidant properties, enhances cellular and humoral immunity, and strengthens the protective function of the body’s mucous membranes.
Lactic acid bacteria are resistant to the antibiotics most commonly used in veterinary practice. They are maximally capable of synthesizing biologically active compounds (organic acids, enzymes, and B vitamins).
Bacilli are not antagonists to lactic acid bacteria, and their metabolites have a wide range of antagonistic activity against pathogens of infectious diseases in animals.
Indications for use
Comprehensive treatment and prevention of animals for diseases of infectious and non-infectious etiology (salmonellosis, colibacillosis, streptococcosis and staphylococcosis, aspergillosis, gastroenteritis, digestive disorders, food and non-food poisoning, stomatitis, tonsillitis, rhinitis, conjunctivitis, and others).
Restoration of microflora after the use of conventional chemotherapy drugs (antibiotics, antiparasitic drugs).
Directed formation and stabilization of healthy saprophytic microflora of the body, normalization of the gastrointestinal tract and metabolism.
Preparation and rehabilitation of animals for physical and stressful loads (competitions, hunting, travel, change of feed, housing conditions, etc.).
Recommendation for use
Before use, “Enteronormin” is dissolved in a prepared aqueous solution of “Yodis+Se” and infused for 16–18 hours at room temperature. Before application, the bottle with the preparation must be shaken, and the solution drawn to the required level in a measuring cup. Using a dosing syringe, administer directly into the animal’s oral cavity. It is also possible to use a laryngeal sprayer or add the preparation to the feed.
Dosage
Adult animals weighing up to 10 kg — 5 ml. Adult animals weighing over 10 kg — 5 ml per 10 kg of body weight. Newborns and sucklings — 5 ml. Teat treatment — 3–5 ml of activated preparation per single treatment.
Method of administration
Comprehensive treatment of animals for infectious and internal non-infectious diseases. Give the activated preparation to the animal orally using a dosing syringe twice a day (at equal intervals). For 7–10 days.
For infectious diseases of the nasopharynx and oral cavity. Spray the affected organs of animals (muzzle, nose, mouth) with the activated preparation two to three times a day. For 5–7 days.
Prevention of infectious diseases, increasing immunity, restoring body microflora when using antibiotics and antiparasitic drugs, during stressful loads (feed change, relocation, weaning), etc. Give the activated preparation to the animal orally using a dosing syringe once a day. For 3–10 days. For newborns and sucklings for the colonization and normalization of microflora. Administer the activated preparation orally using a dosing syringe or a laryngeal sprayer once a day. For 3–5 days.
For normalization of microflora and improvement of the sanitary condition of animal habitats (enclosure, doghouse, cage, etc.). Treat with the activated preparation via aerosol at a rate of 5 ml of 10% solution per 1 m².
In urgent cases (when there is no time to wait for the preparation to activate), such as: poisoning, acute form of gastroenteritis, etc. Pour prepared water over the preparation, mix actively, and immediately give to the animal orally using a dosing syringe. On the first day, administer the preparation every hour, 7–10 doses. Mix the preparation actively before each use. The next day, continue with the regular course (Section No. 1).
Shelf life
Two years. Store the activated preparation in the refrigerator (at a temperature from +3°C to +8°C) in a hermetically sealed bottle for up to 7 days.
Storage and transportation conditions
Dry, dark room at a temperature from +5°C to +25°C.
Instructions for use of “Enteronormin Detox”
RP No. BB-00428-02-12
Composition
Viable bacteria of the genus Enterococcus faecalis — 1×10⁸ CFU/g; viable bacteria of the genus Lactobacillus salivarius — 1×10⁶ CFU/g; viable bacteria of the genus Bacillus subtilis — 1–5×10⁷ CFU/g; chitosan 10%; yeast autolysate 40%; ground mustard 10%; ground garlic 8%; ground cinnamon 7%; zeolite up to 100%.
Pharmaceutical form
Powder from grey-yellow to grey-brown color.
Immunobiological properties
The preparation exhibits antagonistic activity against a wide range of pathogenic bacteria and fungi. It increases appetite and the absorption of feed nutrients and vitamins, which leads to a reduction in feed costs due to the stimulating effect on metabolism by specially selected natural polysaccharides, plant extracts, and the probiotic action of the bacteria included in the preparation.
It has a hepatoprotective effect due to the binding and removal of toxic metabolic products from the digestive tract by the cell walls of the yeast autolysate, which also increases nutrient absorption. It has the property to partially bind and remove mycotoxins (aflatoxin, zearalenone, vomitoxin, ochratoxin) and heavy metals from the body.
It forms normal microflora, thereby normalizing secretory immunity and metabolism, and stabilizing the body’s defenses.
Indications for use
Formation and stabilization of healthy (normal) microflora of the digestive tract of animals and poultry (duodenitis, cholecystitis, enterocolitis, exomyco- and endotoxicosis, colibacillosis). Protection against pathogens of infectious diseases of bacterial and fungal origin: salmonellosis, strepto- and staphylococcosis, aspergillosis, etc.
Method of administration and dosage
Sprinkle on the feed and mix before each feeding. Based on 4 to 6 shakes per 100 grams of feed (from 2 g to 3 g per 1 kg) and give to the animal according to its diet. Add to the feed — constantly.
Shelf life
Two years. Shelf life after the first opening (sampling): one month.
Additional information
Animal species
A wide range of domestic animals and birds.
Contraindications for use
None.
Precautions for use
None.
Interaction with other products
Not compatible with certain antibiotics to which the producer strains are sensitive.
Special instructions during pregnancy and lactation
Not restricted.
Withdrawal period (carencia)
0 days. The preparation does not have a cumulative capacity and does not require a withdrawal period for the use of livestock products.
Side effects
Not established. The preparation does not contain prohibited substances.
Special precautions for persons and operating personnel administering VMP
The preparation does not require protective equipment under conditions of production and use, and does not cause environmental pollution.
Special safety measures for handling unused VMP, methods of its neutralisation and disposal
The preparation does not require protective equipment under conditions of production and use, and does not cause environmental pollution. Disposed of by thermal treatment.
Storage and transportation conditions
Dry, dark room at a temperature from minus 20°C to +25°C.
Name and location of the manufacturer(s)
LLC “SGP “MBS”, 08715, Tsentralna str., 22/1, Kopachiv village, Obukhiv district, Kyiv region. Phone: 0 800 300 008; E-mail: info@sgpmbs.com
Dispensing rules
Without a prescription.
Additional information
If the preparation does not meet the requirements of the package leaflet or complications arise, the use of this series is immediately stopped, and the State Scientific Control Institute of Biotechnology and Microorganism Strains (SSCI BMS) and the supplier (manufacturer) are notified. Simultaneously with a messenger, three unopened bottles of this series of the preparation are sent to the SSCI BMS, in accordance with the “Instructions on the procedure for filing claims for biological preparations intended for use in veterinary medicine” dated 03.06.98 No. 2, at the address: 03151, Kyiv, Donetska str., 30, SSCI BMS.